World
CONTACTStaffCAREER OPPORTUNITIESADVERTISE WITH USPRIVACY POLICYPRIVACY PREFERENCESTERMS OF USELEGAL NOTICE
© 2024 Pride Publishing Inc.
All Rights reserved
All Rights reserved
By continuing to use our site, you agree to our Private Policy and Terms of Use.
A 42-year-old HIV patient with leukemia continues to show no signs of HIV in his blood, two years after a stem cell transplant from a donor with a gene mutation that confers natural resistance to the virus that causes AIDS.
The stunning findings were published Wednesday in The New England Journal of Medicine, according to CNN, but doctors caution that the stem cell treatment is too dangerous to be of routine use to most people infected with HIV.
In the study, reported CNN, "the team deliberately chose a compatible donor who has a naturally occurring gene mutation that confers resistance to HIV. The mutation cripples a receptor known as CCR5, which is normally found on the surface of T cells, the type of immune system cells attacked by HIV.
"The mutation is known as CCR5 delta32 and is found in 1 percent to 3 percent of white populations of European descent.
"HIV uses the CCR5 as a co-receptor (in addition to CD4 receptors) to latch on to and ultimately destroy immune system cells. Since the virus can't gain a foothold on cells that lack CCR5, people who have the mutation have natural protection. (There are other, less common HIV strains that use different co-receptors.)
"People who inherit one copy of CCR5 delta32 take longer to get sick or develop AIDS if infected with HIV. People with two copies (one from each parent) may not become infected at all. The stem cell donor had two copies."
Doctors say that while the risky stem cell transplant option should not be routinely exercised, the findings point the way toward development of potentially safer CCR5-disabling gene therapies or treatments that can be injected into the body.
Want more breaking equality news & trending entertainment stories?
Check out our NEW 24/7 streaming service: the Advocate Channel!
Download the Advocate Channel App for your mobile phone and your favorite streaming device!
From our Sponsors
Most Popular
Here Are Our 2024 Election Predictions. Will They Come True?
November 07 2023 1:46 PM
Meet all 37 of the queer women in this season's WNBA
April 17 2024 11:24 AM
17 Celebs Who Are Out & Proud of Their Trans & Nonbinary Kids
November 30 2023 10:41 AM
Here Are the 15 Most LGBTQ-Friendly Cities in the U.S.
November 01 2023 5:09 PM
Which State Is the Queerest? These Are the States With the Most LGBTQ+ People
December 11 2023 10:00 AM
These 27 Senate Hearing Room Gay Sex Jokes Are Truly Exquisite
December 17 2023 3:33 PM
10 Cheeky and Homoerotic Photos From Bob Mizer's Nude Films
November 18 2023 10:05 PM
42 Flaming Hot Photos From 2024's Australian Firefighters Calendar
November 10 2023 6:08 PM
These Are the 5 States With the Smallest Percentage of LGBTQ+ People
December 13 2023 9:15 AM
Here are the 15 gayest travel destinations in the world: report
March 26 2024 9:23 AM
Watch Now: The Daily
Trending stories from our video partner Advocate Channel.
For more videos and shows go to advocatechannel.com.
Trending stories from our video partner Advocate Channel.
For more videos and shows go to advocatechannel.com.
Latest Stories
How a lesbian's triumph on the Portland Timbers billboard broke barriers
April 24 2024 4:52 PM
‘Faces of Gun Violence’ exhibit unveiled at inaugural survivors’ summit
April 24 2024 4:46 PM
Trans woman Andrea Doria Dos Passos beaten to death in Miami Beach; arrest made
April 24 2024 4:36 PM
TikTok may be banned in the U.S. after Biden signs new law — Why?
April 24 2024 3:43 PM
Serial killer of gay men in New Orleans released after 46 years in prison
April 24 2024 2:16 PM
The 'largest bi+ event in the world' is happening this year. Here's when and where
April 24 2024 12:42 PM
What happens if Donald Trump is jailed for criminal contempt?
April 24 2024 12:22 PM
Megan Rapinoe, Sue Bird, and more urge NCAA to stand up for trans inclusion
April 24 2024 8:00 AM
Over 90% of trans youth live in states pushing anti-trans legislation: report
April 23 2024 10:08 PM