Family Health
International, a group working to promote reproductive and
sexual health around the world, announced Wednesday it is
ending its clinical trial testing Gilead
Sciences' anti-HIV drug Viread as a possible
way to prevent HIV infections among sex workers in Cameroon,
AllAfrica.com reports. The trial was funded by a $6.5
million grant from the Bill and Melinda Gates
Foundation and aimed to gauge whether daily Viread
treatment was effective in preventing HIV infections among
sex workers. Cameroon's health ministry in
February announced that it was suspending the trial
after AIDS activists argued that the sex workers being
recruited for the study were not receiving adequate HIV
prevention information and were not guaranteed HIV
treatment if they became infected during the clinical
trial.
FHI decided to
terminate the trial because of the ongoing opposition to
it and the hold placed on the study by the Cameroon
government. The clinic where the trials are taking
place will be closed in September after the women who
have already enrolled in the study complete their
final health care visits. According to FHI, the five women
who have contracted HIV during the study will receive
long-term access to antiretroviral therapy.
Clinical trials
evaluating Viread's effectiveness in preventing HIV
infections are still under way in Thailand, Malawi, Ghana,
and the United States, but have been called off in
Nigeria and Cambodia because of similar concerns to
those expressed in Cameroon. The U.S. trial includes
sexually active HIV-negative gay men in Atlanta and San
Francisco.