WATCH: Zoey Tur's Tense Exchange With Transphobic Breitbart Editor

A late-night discussion between transgender reporter Zoey Tur and right-wing columnist Ben Shapiro turned tense on Thursday's episode of HLN's Dr. Drew on Call.

The six guests on Dr. Drew Pinsky's show were discussing Caitlyn Jenner's speech at Wednesday night's ESPYs, where she received the Arthur Ashe Award for courage. In what was already bound to be a contentious conversation, Pinsky asked his guests to debate whether Jenner deserved the award.

Inside Edition reporter and helicopter pilot Zoey Tur -- the only out transgender person on the panel -- said she wasn't sure that Jenner deserved a sports-related award so many years after her legendary 1976 gold medal in the Olympic decathlon, but she applauded Jenner's courage nonetheless.

"Being brave is being yourself," says Tur. "And being transgender is about the bravest thing you can do."

That's when Breitbart editor-at-large and noted right-wing pundit Ben Shapiro interjected -- and the trouble started.

"Why are we mainstreaming delusion?" asked Shapiro, before referring to Jenner by her old name and male pronouns.

"It turns out that every chromosome, every cell in Caitlyn Jenner's body is male," Shapiro declared, though he presumably has not obtained a genetic analysis of the Olympian's chromosomes (which aren't inherently gendered, anyway).

As Tur attempted to explain that fact, Shapiro interrupted, asking Tur, "What are your genetics, sir?"

Tur's tone shifted, and she placed a hand behind Shapiro's neck. "You cut that out now," she said. "Or you'll go home in an ambulance."

"That seems mildly inappropriate for a political discussion," Shapiro replied.

The rest of the the commentators laid into Shapiro, calling out his inflammatory comments as clearly intended to be insulting.

But Shapiro continued, apparently unfazed. "It's not a matter of aggressively insulting, he said, returning to his initial point. "The entire discussion is whether we are embracing mental illness and delusion as a society."

After returning from a commercial break, Pinsky gave Tur the floor, to speak about the personal, human cost of being at the center of a media firestorm over one's transition. Stating that such media saturation isn't sustainable, she speculated that "at some point, this all comes crashing down."

"Eventually you find out that you're really in an existential crisis," she continued. "You have to deal with people like [Shapiro], the hatred, that come out against you."

"I don't hate you," Shapiro retorted. "I have sympathy for you."

"No, no, you do hate," Tur replied. "You're consumed with hatred. That's who you are. You're a little man."

Watch both segments below.